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NAD + Depletion Triggers Macrophage Necroptosis, a Cell Death Pathway Exploited by Mycobacterium tuberculosis

July 1, 2021
Abstract Mycobacterium tuberculosis (Mtb) kills infected macrophages by inhibiting apoptosis and promoting necrosis. The tuberculosis necrotizing toxin (TNT) is a secreted nicotinamide adenine dinucleoti…

Critical step found in DNA repair, cellular aging

June 20, 2021
DNA repair is essential for cell vitality, cell survival, and cancer prevention, yet cells’ ability to patch up damaged DNA declines with age for reasons not fully understood. Now, research led by scient…

Pharmacy Compounding Committee Review: Nicotinamide Adenine Dinucleotide (NAD+)

June 17, 2021
FDA Study conducted by the FDA highlights the benefits of NAD treatment specifically reduced stress, anxiety, depression, and decreased effects of drug withdrawls. Read the full article here:  …

Raising NAD in Heart Failure

June 13, 2021
EDITORIAL Raising NAD in Heart Failure Time to Translate? It has long been known that cellular NAD levels are a critical regulator of metabolism and bioenergetics. The intracellular NAD pool consists of …

What is NAD?

June 11, 2021
NAD stands for nicotinamide adenine dinucleotide. It is a coenzyme found in all living cells and has even been called an anti-aging molecule because of its many important roles in promoting health and prolo…

Study explores emerging role of NAD+ in innate and adaptive immune responses

June 6, 2021
In a pre-clinical model, researchers find that NAD+ can trigger a response that protects against lethal infections BRIGHAM AND WOMEN’S HOSPITAL Researchers at Brigham and Women’s Hospital (BWH) have d…

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