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COVID-19: NAD+ deficiency

September 8, 2021
COVID-19: NAD+ deficiency may predispose the aged, obese and type2 diabetics to mortality through its effect on SIRT1 activity Abstract The SARS-CoV-2 hyperinflammatory response is associated with hig…

Rewinding the Clock

July 12, 2021
Treatment restores blood vessel growth, muscle vitality, boosts exercise endurance in aging animals   By EKATERINA PESHEVA March 22, 2018 Research We are as old as our arteries, the adage goes, so…

Intravenous Glutathione Enhances Cycling Time Trial Performance

July 10, 2021
By William Misner Ph.D. ABSTRACT A healthy, fit 61-year old male endurance athlete received four (4 each) intravenous glutathione treatments consisting of 100 mg/cc, using 10cc (total 1000 milligrams)…

Emerging potential benefits of modulating NAD+ metabolism in cardiovascular disease

July 9, 2021
Abstract Nicotinamide adenine dinucleotide (NAD+) and related metabolites are central mediators of fuel oxidation and bioenergetics within cardiomyocytes. Additionally, NAD+ is required for the activity …

NAD+ Metabolism as an Emerging Therapeutic Target for Cardiovascular Diseases Associated With Sudden Cardiac Death

July 8, 2021
Abstract In addition to its central role in mediating oxidation reduction in fuel metabolism and bioenergetics, nicotinamide adenine dinucleotide (NAD+) has emerged as a vital co-substrate for a number o…

NAD+ and sirtuins in aging and disease

July 7, 2021
Abstract Nicotinamide adenine dinucleotide (NAD(+)) is a classical coenzyme mediating many redox reactions. NAD(+) also plays an important role in the regulation of NAD(+)-consuming enzymes, including si…

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