Tag: heart failure

Raising NAD in Heart Failure

EDITORIAL
Raising NAD in Heart Failure
Time to Translate?

It has long been known that cellular NAD levels are a critical regulator of metabolism and bioenergetics. The intracellular NAD pool consists of both oxidized (NAD+) and reduced forms (NADH). NAD+ is the main hydride acceptor in intermediary metabolism. Electrons derived from substrate catabolism are carried by NADH and used for oxidative phosphorylation and biosynthetic reactions. These reduction-oxidation reactions are not only essential for mitochondrial function and cell metabolism but also serve as important modulators of cell signaling.1,2 NAD+ functions as a cosubstrate for sirtuin deacylases, ADP-ribose transferases, and cyclic ADP-ribose synthases that govern posttranslational modification of proteins, DNA repair, and inflammatory responses.

Link to full article:  https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.117.032626


Statements provided have not been evaluated by the Food and Drug Administration. We do not diagnose, prevent or cure any medical conditions. All infusions and injections are administered by state licensed registered nurses and overseen by our Medical Director, Dr. Daniel La Perriere, a board certified MD, Certified Functional Medicine practitioner through the IFM and Founder of Colorado Concierge Functional Medicine. Some health conditions contraindicate the use of our products. Please consult your physician before beginning injections of any kind.

Cancellation policy for blood draws: Please contact us to cancel your appointment at least 24 hours prior to your appointment. No call/no show or day-of cancellations will be charged full price of appointment.

Cancellation policy for IV: Please contact us to cancel your appointment at least 24 hours prior to your appointment. No call/no show will be billed at full price. You may reschedule your appointment with no fee. Day-of cancellation without reschedule will be billed $50.